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» Optimizing Multiple Spaced Seeds for Homology Search
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ICTAI
2002
IEEE
14 years 14 days ago
Calculus of Variations in Discrete Space for Constrained Nonlinear Dynamic Optimization
In this paper, we propose new dominance relations that can speed up significantly the solution process of nonlinear constrained dynamic optimization problems in discrete time and...
Yixin Chen, Benjamin W. Wah
IJCAI
2001
13 years 9 months ago
Exploiting Multiple Secondary Reinforcers in Policy Gradient Reinforcement Learning
Most formulations of Reinforcement Learning depend on a single reinforcement reward value to guide the search for the optimal policy solution. If observation of this reward is rar...
Gregory Z. Grudic, Lyle H. Ungar
IPPS
2010
IEEE
13 years 5 months ago
Large neighborhood local search optimization on graphics processing units
Local search (LS) algorithms are among the most powerful techniques for solving computationally hard problems in combinatorial optimization. These algorithms could be viewed as &q...
Thé Van Luong, Nouredine Melab, El-Ghazali ...
GECCO
2006
Springer
132views Optimization» more  GECCO 2006»
13 years 11 months ago
"Optimal" mutation rates for genetic search
Using a set of model landscapes we examine how different mutation rates affect different search metrics. We show that very universal heuristics, such as 1/N and the error threshol...
Jorge Cervantes, Christopher R. Stephens
WABI
2005
Springer
117views Bioinformatics» more  WABI 2005»
14 years 1 months ago
Faster Algorithms for Optimal Multiple Sequence Alignment Based on Pairwise Comparisons
Multiple Sequence Alignment (MSA) is one of the most fundamental problems in computational molecular biology. The running time of the best known scheme for finding an optimal ali...
Pankaj K. Agarwal, Yonatan Bilu, Rachel Kolodny