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WABI
2007
Springer
123views Bioinformatics» more  WABI 2007»
14 years 1 months ago
Inverse Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Eagu Kim, John D. Kececioglu
BMCBI
2008
163views more  BMCBI 2008»
13 years 7 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
CANDC
2005
ACM
13 years 7 months ago
MSAID: multiple sequence alignment based on a measure of information discrepancy
We propose an algorithm of global multiple sequence alignment that is based on a measure of what we call information discrepancy. The algorithm follows a progressive alignment ite...
Min Zhang, Weiwu Fang, Junhua Zhang, Zhongxian Chi
GECCO
2005
Springer
112views Optimization» more  GECCO 2005»
14 years 1 months ago
A multiple objective evolutionary algorithm for multiple sequence alignment
The problem of multiple sequence alignment is important for bioinformatics. This problem is widely studied and a popular tool to solve this problem is Clustal X. This work introdu...
Pasut Seeluangsawat, Prabhas Chongstitvatana
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 1 months ago
TreeRefiner: A Tool for Refining a Multiple Alignment on a Phylogenetic Tree
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
Aswath Manohar, Serafim Batzoglou