Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
Peter D. Karp, Suzanne M. Paley, Markus Krummenack...
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...