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BMCBI
2010
13 years 2 months ago
2010
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
BMCBI
2010
13 years 2 months ago
2010
Background: Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is ent...
BMCBI
2011
13 years 2 months ago
2011
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
BMCBI
2011
13 years 2 months ago
2011
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
BMCBI
2011
13 years 2 months ago
2011
Background: We present a novel method to encode ambiguously aligned regions in fixed multiple sequence alignments by ‘Pairwise Identity and Cost Scores Ordination’ (PICS-Ord)....