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» Parallel Assembler for Fuzzy Genome Sequence Assembly
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RECOMB
2001
Springer
14 years 11 months ago
A new approach to fragment assembly in DNA sequencing
For the last twenty years fragment assembly in DNA sequencing followed the "overlap - layout - consensus" paradigm that is used in all currently available assembly tools...
Pavel A. Pevzner, Haixu Tang, Michael S. Waterman
RECOMB
2001
Springer
14 years 3 months ago
The greedy path-merging algorithm for sequence assembly
Two different approaches to determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly-funded Human Genome Proje...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
WABI
2009
Springer
156views Bioinformatics» more  WABI 2009»
14 years 5 months ago
Phylogenetic Comparative Assembly
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Peter Husemann, Jens Stoye
BMCBI
2011
13 years 5 months ago
Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies
Background: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improve...
Joshua Wetzel, Carl Kingsford, Mihai Pop
GCB
2004
Springer
92views Biometrics» more  GCB 2004»
14 years 4 months ago
Syntenic Layout of Two Assemblies of Related Genomes
: To facilitate research in comparative genomics, sequencing projects are increasingly aimed at assembling the genomes of closely related organisms. Given two incomplete assemblies...
Olaf Delgado Friedrichs, Aaron L. Halpern, Ross Li...