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BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2008
114views more  BMCBI 2008»
13 years 8 months ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...
IPPS
2007
IEEE
14 years 2 months ago
RNAVLab: A unified environment for computational RNA structure analysis based on grid computing technology
Ribonucleic acid (RNA) molecules play important roles in many biological processes including gene expression and regulation. An RNA molecule is a linear polymer which folds back o...
Michela Taufer, Ming-Ying Leung, Kyle L. Johnson, ...
ICSM
2007
IEEE
14 years 2 months ago
A Maintainable Software Architecture for Fast and Modular Bioinformatics Sequence Search
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
Jeremy S. Archuleta, Eli Tilevich, Wu-chun Feng
CIBCB
2009
IEEE
13 years 9 months ago
rnaDesign: Local search for RNA secondary structure design
Abstract-- The RNA secondary structure design (SSD) problem is a recently emerging research topic motivated by applications such as customized drug design and the self-assembly of ...
Denny C. Dai, Herbert H. Tsang, Kay C. Wiese