Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families...
Sudhir Kumar, Masatoshi Nei, Joel Dudley, Koichiro...
Computing large multiple protein sequence alignments using progressive alignment tools such as ClustalW requires several hours on state-of-the-art workstations. ClustalW uses a th...
: Accurate reconstruction of phylogenetic trees very often involves solving hard optimization problems, particularly the maximum parsimony (MP) and maximum likelihood (ML) problems...
Cristian Coarfa, Yuri Dotsenko, John M. Mellor-Cru...
Parallel scalability allows an application to efficiently utilize an increasing number of processing elements. In this paper we explore a design space for parallel scalability for...