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PROCEDIA
2010
154views more  PROCEDIA 2010»
13 years 1 months ago
Parallel computation of phylogenetic consensus trees
The field of bioinformatics is witnessing a rapid and overwhelming accumulation of molecular sequence data, predominantly driven by novel wet-lab sequencing techniques. This trend...
Andre J. Aberer, Nicholas D. Pattengale, Alexandro...
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
13 years 7 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
BMCBI
2010
142views more  BMCBI 2010»
13 years 7 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
IPPS
2006
IEEE
14 years 1 months ago
Phylogenetic models of rate heterogeneity: a high performance computing perspective
Inference of phylogenetic trees using the maximum likelihood (ML) method is NP-hard. Furthermore, the computation of the likelihood function for huge trees of more than 1,000 orga...
Alexandros Stamatakis
ICPP
2009
IEEE
14 years 1 months ago
Load Balance in the Phylogenetic Likelihood Kernel
—Recent advances in DNA sequencing techniques have led to an unprecedented accumulation and availability of molecular sequence data that needs to be analyzed. This data explosion...
Alexandros Stamatakis, Michael Ott