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IWANN
2009
Springer
14 years 2 months ago
ZARAMIT: A System for the Evolutionary Study of Human Mitochondrial DNA
Abstract. ZARAMIT is an information system capable of fully automated phylogeny reconstruction. Methods have been tailored to mitochondrial DNA sequences, with focus on subproblem ...
Roberto Blanco, Elvira Mayordomo
ISAAC
2003
Springer
70views Algorithms» more  ISAAC 2003»
14 years 27 days ago
Settling the Intractability of Multiple Alignment
In this paper some of the most fundamental problems in computational biology are proved intractable. The following problems are shown NP-hard for all binary or larger alphabets und...
Isaac Elias
CORR
2011
Springer
235views Education» more  CORR 2011»
13 years 2 months ago
On the accuracy of language trees
Historical linguistics aims at inferring the most likely language phylogenetic tree starting from information concerning the evolutionary relatedness of languages. The available i...
Simone Pompei, Vittorio Loreto, Francesca Tria
CPM
2009
Springer
122views Combinatorics» more  CPM 2009»
14 years 2 months ago
Haplotype Inference Constrained by Plausible Haplotype Data
The haplotype inference problem (HIP) asks to find a set of haplotypes which resolve a given set of genotypes. This problem is of enormous importance in many practical fields, su...
Michael R. Fellows, Tzvika Hartman, Danny Hermelin...
ICCS
2001
Springer
14 years 5 days ago
High-Performance Algorithm Engineering for Computational Phylogenetics
Abstract. Phylogeny reconstruction from molecular data poses complex optimization problems: almost all optimization models are NP-hard and thus computationally intractable. Yet app...
Bernard M. E. Moret, David A. Bader, Tandy Warnow