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» Parameters for accurate genome alignment
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BMCBI
2008
80views more  BMCBI 2008»
13 years 7 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...
CIBB
2008
13 years 9 months ago
Analysis of Kernel Based Protein Classification Strategies Using Pairwise Sequence Alignment Measures
Abstract. We evaluated methods of protein classification that use kernels built from BLAST output parameters. Protein sequences were represented as vectors of parameters (e.g. simi...
Dino Franklin, Somdutta Dhir, Sándor Pongor
JCB
2008
52views more  JCB 2008»
13 years 7 months ago
Spectrum-Based De Novo Repeat Detection in Genomic Sequences
A novel approach to the detection of genomic repeats is presented in this paper. The technique, dubbed SAGRI (Spectrum Assisted Genomic Repeat Identifier), is based on the spectru...
Huy Hoang Do, Kwok Pui Choi, Franco P. Preparata, ...
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
RECOMB
2001
Springer
14 years 7 months ago
Algorithms for phylogenetic footprinting
Phylogenetic footprinting is a comparative genomics approach for predicting transcription factor binding sites, where a set of orthologous regulatory regions are compared and short...
Mathieu Blanchette