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DATAMINE
2008
143views more  DATAMINE 2008»
13 years 8 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
AMC
2006
67views more  AMC 2006»
13 years 8 months ago
A general probabilistic model of the PCR process
Earlier work by Saha et al. rigorously derived a general probabilistic model for the PCR process that includes as a special case the Velikanov-Kapral model where all nucleotide re...
Nilanjan Saha, Layne T. Watson, Karen Kafadar, Ale...
BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
On single and multiple models of protein families for the detection of remote sequence relationships
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
James A. Casbon, Mansoor A. S. Saqi
BMCBI
2006
152views more  BMCBI 2006»
13 years 8 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2006
195views more  BMCBI 2006»
13 years 8 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona