Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
Yaping Feng, Andrzej Kloczkowski, Robert L. Jernig...
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...