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ISMB
1994
13 years 8 months ago
An Efficient Method for Multiple Sequence Alignment
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Jin Kim, Sakti Pramanik
BMCBI
2005
93views more  BMCBI 2005»
13 years 7 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
RECOMB
1997
Springer
13 years 11 months ago
Progressive multiple alignment with constraints
A progressive alignment algorithm produces a multi-alignment of a set of sequences by repeatedly aligning pairs of sequences and/or previously generated alignments. We describe a ...
Gene Myers, Sanford Selznick, Zheng Zhang 0004, We...