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BMCBI
2005
102views more  BMCBI 2005»
13 years 7 months ago
Genomic multiple sequence alignments: refinement using a genetic algorithm
Background: Genomic sequence data cannot be fully appreciated in isolation. Comparative genomics
Chunlin Wang, Elliot J. Lefkowitz
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
14 years 2 months ago
ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...
AAAI
2004
13 years 9 months ago
PROBCONS: Probabilistic Consistency-Based Multiple Alignment of Amino Acid Sequences
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
Chuong B. Do, Michael Brudno, Serafim Batzoglou
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
14 years 27 days ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye
IPL
2007
96views more  IPL 2007»
13 years 7 months ago
On constructing an optimal consensus clustering from multiple clusterings
Computing a suitable measure of consensus among several clusterings on the same data is an important problem that arises in several areas such as computational biology and data mi...
Piotr Berman, Bhaskar DasGupta, Ming-Yang Kao, Jie...