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WABI
2004
Springer
132views Bioinformatics» more  WABI 2004»
14 years 24 days ago
Joint Analysis of DNA Copy Numbers and Gene Expression Levels
Abstract. Genomic instabilities, amplifications, deletions and translocations are often observed in tumor cells. In the process of cancer pathogenesis cells acquire multiple genom...
Doron Lipson, Amir Ben-Dor, Elinor Dehan, Zohar Ya...
BMCBI
2006
117views more  BMCBI 2006»
13 years 7 months ago
Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comf
Background: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock...
Nan Mei, Lei Guo, Lu Zhang 0013, Leming M. Shi, Yo...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
BMCBI
2011
13 years 2 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...