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BIODATAMINING
2008
178views more  BIODATAMINING 2008»
13 years 7 months ago
Clustering-based approaches to SAGE data mining
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Haiying Wang, Huiru Zheng, Francisco Azuaje
BIODATAMINING
2008
147views more  BIODATAMINING 2008»
13 years 7 months ago
Neural networks for genetic epidemiology: past, present, and future
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
Alison A. Motsinger-Reif, Marylyn D. Ritchie
BIODATAMINING
2008
135views more  BIODATAMINING 2008»
13 years 7 months ago
Fast Gene Ontology based clustering for microarray experiments
Background: Analysis of a microarray experiment often results in a list of hundreds of diseaseassociated genes. In order to suggest common biological processes and functions for t...
Kristian Ovaska, Marko Laakso, Sampsa Hautaniemi
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
122views more  BMCBI 2010»
13 years 7 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen