Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
Recently, profile context-sensitive HMMs (profile-csHMMs) have been proposed which are very effective in modeling the common patterns and motifs in related symbol sequences. Pro...
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
We present an index structure for managing weightedsequences in large databases. A weighted-sequence is defined as a two-dimensional structure where each element in the sequence i...
In previous work [10], we considered algorithms related to the statistics of matches with words and regular expressions in texts generated by Bernoulli or Markov sources. In this w...