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» Patterns of Component Evolution
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BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...
BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
BMCBI
2006
78views more  BMCBI 2006»
13 years 7 months ago
Modelling study of dimerization in mammalian defensins
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
Anita Suresh, Chandra Verma
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
CCR
2006
118views more  CCR 2006»
13 years 7 months ago
Tmix: a tool for generating realistic TCP application workloads in ns-2
In order to perform realistic network simulations, one needs a traffic generator that is capable of generating realistic synthetic traffic in a closed-loop fashion that "look...
Michele C. Weigle, Prashanth Adurthi, Félix...