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BMCBI
2006
145views more  BMCBI 2006»
13 years 7 months ago
Querying the public databases for sequences using complex keywords contained in the feature lines
Background: High throughput technologies often require the retrieval of large data sets of sequences. Retrieval of EMBL or GenBank entries using keywords is easy using tools such ...
Olivier Croce, Michaël Lamarre, Richard Chris...
BMCBI
2006
195views more  BMCBI 2006»
13 years 7 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
BMCBI
2006
201views more  BMCBI 2006»
13 years 7 months ago
Gene selection algorithms for microarray data based on least squares support vector machine
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
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