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» Performance Analysis of Sequence Alignment Applications
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RECOMB
2003
Springer
14 years 9 months ago
Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals
We propose a framework for modeling sequence motifs based on the maximum entropy principle (MEP). We recommend approximating short sequence motif distributions with the maximum en...
Gene W. Yeo, Christopher B. Burge
BMCBI
2010
131views more  BMCBI 2010»
13 years 4 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
BMCBI
2011
13 years 4 months ago
PileLine: a toolbox to handle genome position information in next-generation sequencing studies
Background: Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of approp...
Daniel Glez-Peña, Gonzalo Gómez-L&oa...
SC
2009
ACM
14 years 1 months ago
Cloud technologies for bioinformatics applications
Executing large number of independent tasks or tasks that perform minimal inter-task communication in parallel is a common requirement in many domains. In this paper, we present o...
Xiaohong Qiu, Jaliya Ekanayake, Scott Beason, Thil...
BMCBI
2010
148views more  BMCBI 2010»
13 years 9 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...