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» Performance Analysis of Sequence Alignment Applications
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BMCBI
2008
122views more  BMCBI 2008»
13 years 9 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
14 years 2 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye
BMCBI
2008
163views more  BMCBI 2008»
13 years 9 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
JCSS
2002
95views more  JCSS 2002»
13 years 8 months ago
Efficient algorithms for locating the length-constrained heaviest segments with applications to biomolecular sequence analysis
We study two fundamental problems concerning the search for interesting regions in sequences: (i) given a sequence of real numbers of length n and an upper bound U; find a consecu...
Yaw-Ling Lin, Tao Jiang, Kun-Mao Chao
CIBB
2008
13 years 11 months ago
Analysis of Kernel Based Protein Classification Strategies Using Pairwise Sequence Alignment Measures
Abstract. We evaluated methods of protein classification that use kernels built from BLAST output parameters. Protein sequences were represented as vectors of parameters (e.g. simi...
Dino Franklin, Somdutta Dhir, Sándor Pongor