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TCBB
2008
126views more  TCBB 2008»
15 years 4 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
IPM
2007
143views more  IPM 2007»
15 years 4 months ago
QCS: A system for querying, clustering and summarizing documents
Information retrieval systems consist of many complicated components. Research and development of such systems is often hampered by the difficulty in evaluating how each particula...
Daniel M. Dunlavy, Dianne P. O'Leary, John M. Conr...
BMCBI
2005
89views more  BMCBI 2005»
15 years 4 months ago
An empirical analysis of training protocols for probabilistic gene finders
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
William H. Majoros, Steven Salzberg
BMCBI
2005
135views more  BMCBI 2005»
15 years 4 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2005
94views more  BMCBI 2005»
15 years 4 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
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