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» Permutative Additives and Exponentials
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BMCBI
2010
70views more  BMCBI 2010»
13 years 7 months ago
The Text-mining based PubChem Bioassay neighboring analysis
Background: In recent years, the number of High Throughput Screening (HTS) assays deposited in PubChem has grown quickly. As a result, the volume of both the structured informatio...
Lianyi Han, Tugba O. Suzek, Yanli Wang, Steve H. B...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2008
75views more  BMCBI 2008»
13 years 7 months ago
Re-searcher: a system for recurrent detection of homologous protein sequences
Background: Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence s...
Valdemaras Repsys, Mindaugas Margelevicius, Ceslov...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...