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BMCBI
2010
76views more  BMCBI 2010»
13 years 7 months ago
Validation and characterization of DNA microarray gene expression data distribution and associated moments
Background: The data from DNA microarrays are increasingly being used in order to understand effects of different conditions, exposures or diseases on the modulation of the expres...
Reuben Thomas, Luis de la Torre, Xiaoqing Chang, S...
CIKM
2010
Springer
13 years 6 months ago
A hierarchical approach to reachability query answering in very large graph databases
The cost of reachability query computation using traditional algorithms such as depth first search or transitive closure has been found to be prohibitive and unacceptable in mass...
Saikat K. Dey, Hasan M. Jamil
BMCBI
2008
181views more  BMCBI 2008»
13 years 6 months ago
Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
ICPPW
2009
IEEE
13 years 5 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...