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» PiQA: An Algebra for Querying Protein Data Sets
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CSR
2006
Springer
13 years 11 months ago
Fast Motif Search in Protein Sequence Databases
Regular expression pattern matching is widely used in computational biology. Searching through a database of sequences for a motif (a simple regular expression), or its variations...
Elena Zheleva, Abdullah N. Arslan
ICDE
2008
IEEE
191views Database» more  ICDE 2008»
14 years 8 months ago
An Algebraic Approach to Rule-Based Information Extraction
Traditional approaches to rule-based information extraction (IE) have primarily been based on regular expression grammars. However, these grammar-based systems have difficulty scal...
Frederick Reiss, Sriram Raghavan, Rajasekar Krishn...
JMLR
2012
11 years 9 months ago
Active Clustering of Biological Sequences
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
BMCBI
2010
121views more  BMCBI 2010»
13 years 7 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein