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BMCBI
2008
111views more  BMCBI 2008»
13 years 11 months ago
VisualRepbase: an interface for the study of occurrences of transposable element families
Background: Repbase is a reference database of eukaryotic repetitive DNA, which includes prototypic sequences of repeats and basic information described in annotations. Repbase al...
Sébastien Tempel, Matthew Jurka, Jerzy Jurk...
BMCBI
2007
97views more  BMCBI 2007»
13 years 11 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2008
128views more  BMCBI 2008»
13 years 11 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2008
105views more  BMCBI 2008»
13 years 11 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2007
91views more  BMCBI 2007»
13 years 11 months ago
A machine learning approach for the identification of odorant binding proteins from sequence-derived properties
Background: Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as od...
Ganesan Pugalenthi, E. Ke Tang, Ponnuthurai N. Sug...