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BMCBI
2006
88views more  BMCBI 2006»
13 years 11 months ago
Protein kinases associated with the yeast phosphoproteome
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Ross I. Brinkworth, Alan L. Munn, Bostjan Kobe
BMCBI
2006
101views more  BMCBI 2006»
13 years 11 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
BMCBI
2006
93views more  BMCBI 2006»
13 years 11 months ago
Evaluation of absolute quantitation by nonlinear regression in probe-based real-time PCR
Background: In real-time PCR data analysis, the cycle threshold (CT) method is currently the gold standard. This method is based on an assumption of equal PCR efficiency in all re...
Rasmus Goll, Trine Olsen, Guanglin Cui, Jon Florho...
BMCBI
2006
137views more  BMCBI 2006»
13 years 11 months ago
Chaos game representation for comparison of whole genomes
Background: Chaos game representation of genome sequences has been used for visual representation of genome sequence patterns as well as alignment-free comparisons of sequences ba...
Jijoy Joseph, Roschen Sasikumar
BMCBI
2006
74views more  BMCBI 2006»
13 years 11 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane