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    BMCBI
    2008
    126views more  BMCBI 2008»
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    13 years 9 months ago
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
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    Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
    Katerina Kechris, Hao Li
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    BMCBI
    2008
    119views more  BMCBI 2008»
    A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
    13 years 9 months ago
    A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
    Download  www.biomedcentral.com
    Background: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differe...
    Sabine Pérès, Laurence Molina, Nicol...
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    BMCBI
    2008
    102views more  BMCBI 2008»
    Improving protein function prediction methods with integrated literature data
    13 years 9 months ago
    Improving protein function prediction methods with integrated literature data
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    Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
    Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
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    BMCBI
    2008
    123views more  BMCBI 2008»
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    13 years 9 months ago
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    Download  www.biomedcentral.com
    Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
    Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
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    BMCBI
    2008
    121views more  BMCBI 2008»
    ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
    13 years 9 months ago
    ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
    Download  www.biomedcentral.com
    Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
    Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
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