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BMCBI
2006
103views more  BMCBI 2006»
13 years 9 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2006
114views more  BMCBI 2006»
13 years 9 months ago
Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa
Background: Pseudomonas aeruginosa, an opportunistic pathogen, is often encountered in chronic lung diseases such as cystic fibrosis or chronic obstructive pneumonia, as well as a...
Didier Filopon, Annabelle Mérieau, Gilles B...
BMCBI
2006
119views more  BMCBI 2006»
13 years 9 months ago
Evaluation of microarray data normalization procedures using spike-in experiments
Background: Recently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-ca...
Patrik Rydén, Henrik Andersson, Mattias Lan...
BMCBI
2006
128views more  BMCBI 2006»
13 years 9 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2006
114views more  BMCBI 2006»
13 years 9 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
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