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BMCBI
2006
13 years 8 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
BMCBI
2006
13 years 8 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
BMCBI
2006
13 years 8 months ago
2006
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
BMCBI
2006
13 years 8 months ago
2006
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
BMCBI
2006
13 years 8 months ago
2006
Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way...