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BMCBI
2010
148views more  BMCBI 2010»
13 years 8 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
121views more  BMCBI 2010»
13 years 8 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
EOR
2006
135views more  EOR 2006»
13 years 8 months ago
Principles of scatter search
Scatter search is an evolutionary method that has been successfully applied to hard optimization problems. The fundamental concepts and principles of the method were first propose...
Rafael Martí, Manuel Laguna, Fred Glover
SADM
2010
141views more  SADM 2010»
13 years 3 months ago
A parametric mixture model for clustering multivariate binary data
: The traditional latent class analysis (LCA) uses a mixture model with binary responses on each subject that are independent conditional on cluster membership. However, in many pr...
Ajit C. Tamhane, Dingxi Qiu, Bruce E. Ankenman
PVLDB
2011
12 years 11 months ago
An Incremental Hausdorff Distance Calculation Algorithm
The Hausdorff distance is commonly used as a similarity measure between two point sets. Using this measure, a set X is considered similar to Y iff every point in X is close to at ...
Sarana Nutanong, Edwin H. Jacox, Hanan Samet