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BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
14 years 1 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 7 months ago
Globally, unrelated protein sequences appear random
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
Daniel T. Lavelle, William R. Pearson
BMCBI
2008
93views more  BMCBI 2008»
13 years 7 months ago
VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens
Background: Prediction of bacterial virulent protein sequences has implications for identification and characterization of novel virulence-associated factors, finding novel drug/v...
Aarti Garg, Dinesh Gupta
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...