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OOPSLA
2005
Springer
14 years 1 months ago
Improving architecture testability with patterns
There is a critical need for approaches to support software testing. Our research exploits the information described at Architectural Patterns to drive the definition of tests. As...
Roberta Coelho, Uirá Kulesza, Arndt von Sta...
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
A mixture of feature experts approach for protein-protein interaction prediction
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Yanjun Qi, Judith Klein-Seetharaman, Ziv Bar-Josep...
BMCBI
2008
129views more  BMCBI 2008»
13 years 8 months ago
Prediction of the outcome of preoperative chemotherapy in breast cancer using DNA probes that provide information on both comple
Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
René Natowicz, Roberto Incitti, Euler Guima...