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BMCBI
2008
86views more  BMCBI 2008»
13 years 9 months ago
Predicting protein linkages in bacteria: Which method is best depends on task
Background: Applications of computational methods for predicting protein functional linkages are increasing. In recent years, several bacteria-specific methods for predicting link...
Anis Karimpour-Fard, Sonia M. Leach, Ryan T. Gill,...
JBI
2006
107views Bioinformatics» more  JBI 2006»
13 years 8 months ago
Knowledge guided analysis of microarray data
To microarray expression data analysis, it is well accepted that biological knowledge-guided clustering techniques show more advantages than pure mathematical techniques. In this ...
Zhuo Fang, Jiong Yang, Yixue Li, Qing-ming Luo, Le...
BMCBI
2010
240views more  BMCBI 2010»
13 years 9 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
BMCBI
2010
96views more  BMCBI 2010»
13 years 9 months ago
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
Background: Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standar...
Lihua J. Zhu, Claude Gazin, Nathan D. Lawson, Herv...
BMCBI
2010
84views more  BMCBI 2010»
13 years 9 months ago
Testing the additional predictive value of high-dimensional molecular data
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Anne-Laure Boulesteix, Torsten Hothorn