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BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
ISMB
2007
13 years 11 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
BIOCOMP
2007
13 years 10 months ago
Prediction of trans-antisense Transcripts in Arabidopsis thaliana
Background: Natural antisense transcripts (NATs) are coding or non-coding RNAs with sequence complementarity to other transcripts (sense transcripts). These RNAs could potentially...
Huan Wang, Nam-Hai Chua, Xiu-Jie Wang
BMCBI
2007
203views more  BMCBI 2007»
13 years 8 months ago
A Grid-based solution for management and analysis of microarrays in distributed experiments
Several systems have been presented in the last years in order to manage the complexity of large microarray experiments. Although good results have been achieved, most systems ten...
Ivan Porro, Livia Torterolo, Luca Corradi, Marco F...
BMCBI
2006
105views more  BMCBI 2006»
13 years 8 months ago
Integrative investigation of metabolic and transcriptomic data
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Pinar Pir, Betül Kirdar, Andrew Hayes, Z. Ils...