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BMCBI
2006
184views more  BMCBI 2006»
13 years 8 months ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...
BMCBI
2005
117views more  BMCBI 2005»
13 years 8 months ago
Differentiation of regions with atypical oligonucleotide composition in bacterial genomes
Background: Complete sequencing of bacterial genomes has become a common technique of present day microbiology. Thereafter, data mining in the complete sequence is an essential st...
Oleg N. Reva, Burkhard Tümmler
BMCBI
2006
98views more  BMCBI 2006»
13 years 8 months ago
Scanning sequences after Gibbs sampling to find multiple occurrences of functional elements
Background: Many DNA regulatory elements occur as multiple instances within a target promoter. Gibbs sampling programs for finding DNA regulatory elements de novo can be prohibiti...
Kannan Tharakaraman, Leonardo Mariño-Ram&ia...
GECCO
2005
Springer
146views Optimization» more  GECCO 2005»
14 years 2 months ago
An empirical study of the robustness of two module clustering fitness functions
Two of the attractions of search-based software engineering (SBSE) derive from the nature of the fitness functions used to guide the search. These have proved to be highly robust...
Mark Harman, Stephen Swift, Kiarash Mahdavi
BMCBI
2005
102views more  BMCBI 2005»
13 years 8 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...