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BMCBI
2008
89views more  BMCBI 2008»
13 years 8 months ago
Increasing the efficiency of bacterial transcription simulations: When to exclude the genome without loss of accuracy
Background: Simulating the major molecular events inside an Escherichia coli cell can lead to a very large number of reactions that compose its overall behaviour. Not only should ...
Marco A. J. Iafolla, Guang Qiang Dong, David R. Mc...
BMCBI
2007
151views more  BMCBI 2007»
13 years 8 months ago
The Genopolis Microarray Database
Background: Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. ...
Andrea Splendiani, Marco Brandizi, Gael Even, Otta...
BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
BMCBI
2007
133views more  BMCBI 2007»
13 years 8 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2005
94views more  BMCBI 2005»
13 years 8 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya