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BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo
BMCBI
2008
126views more  BMCBI 2008»
13 years 9 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
BMCBI
2005
84views more  BMCBI 2005»
13 years 8 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
GFKL
2005
Springer
141views Data Mining» more  GFKL 2005»
14 years 2 months ago
On External Indices for Mixtures: Validating Mixtures of Genes
Mixture models represent results of gene expression cluster analysis in a more natural way than ’hard’ partitions. This is also true for the representation of gene labels, such...
Ivan G. Costa, Alexander Schliep
BMCBI
2008
102views more  BMCBI 2008»
13 years 9 months ago
Monitoring the evolutionary aspect of the Gene Ontology to enhance predictability and usability
Background: Much effort is currently made to develop the Gene Ontology (GO). Due to the dynamic nature of information it addresses, GO undergoes constant updates whose results are...
Jong C. Park, Tak-eun Kim, Jinah Park