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RECOMB
2005
Springer
14 years 9 months ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola
BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
CIARP
2009
Springer
14 years 3 months ago
Analysis of the GRNs Inference by Using Tsallis Entropy and a Feature Selection Approach
Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Fabrício Martins Lopes, Evaldo A. de Olivei...
BIOCOMP
2006
13 years 10 months ago
A Heuristic Approach to Scoring Gene Clustering Algorithms
In the past decades, many clustering algorithms have been proposed for the analysis of gene expression data, but little guidance is available to help choose among them. Given the ...
Longde Yin, Chun-Hsi Huang
IJCNN
2008
IEEE
14 years 3 months ago
Dataset complexity can help to generate accurate ensembles of k-nearest neighbors
— Gene expression based cancer classification using classifier ensembles is the main focus of this work. A new ensemble method is proposed that combines predictions of a small ...
Oleg Okun, Giorgio Valentini