Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
Background: Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) a...
Franck Rapaport, Andrei Zinovyev, Marie Dutreix, E...
Regulatory cascades consisting of stress-induced gene modules and their transcriptional regulators were recently identified and quantitatively modeled using Artificial Neural Netwo...
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...