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» Predicting Peroxisomal Proteins
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BMCBI
2005
143views more  BMCBI 2005»
13 years 8 months ago
Evaluation of BioCreAtIvE assessment of task 2
Background: Molecular Biology accumulated substantial amounts of data concerning functions of genes and proteins. Information relating to functional descriptions is generally extr...
Christian Blaschke, Eduardo Andrés Le&oacut...
CDC
2009
IEEE
141views Control Systems» more  CDC 2009»
13 years 6 months ago
Cell design in bacteria as a convex optimization problem
In this paper, we investigate the cell design of bacteria during the exponential growth. To this purpose, we propose to formulate the problem as a non differentiable convex optimiz...
Anne Goelzer, Vincent Fromion, Gérard Scorl...
TCBB
2011
13 years 3 months ago
Semi-Markov Models for Brownian Dynamics Permeation in Biological Ion Channels
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
Vikram Krishnamurthy, Kai Yiu Luk
BMCBI
2008
172views more  BMCBI 2008»
13 years 8 months ago
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
Pelin Armutlu, Muhittin Emre Ozdemir, Fadime Ü...
GCB
1997
Springer
74views Biometrics» more  GCB 1997»
14 years 10 days ago
Using constraint programming for lattice protein folding
We present a global search technique for nding the global minimal conformation of a sequence in Dill's HP-lattice model5;6 . The HP-lattice model is a simpli ed model of prot...
Rolf Backofen