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BMCBI
2010
144views more  BMCBI 2010»
13 years 10 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
KDD
2008
ACM
213views Data Mining» more  KDD 2008»
14 years 10 months ago
Heterogeneous data fusion for alzheimer's disease study
Effective diagnosis of Alzheimer's disease (AD) is of primary importance in biomedical research. Recent studies have demonstrated that neuroimaging parameters are sensitive a...
Jieping Ye, Kewei Chen, Teresa Wu, Jing Li, Zheng ...
BMCBI
2005
201views more  BMCBI 2005»
13 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
ISMB
2001
13 years 11 months ago
Molecular classification of multiple tumor types
Using gene expression data to classify tumor types is a very promising tool in cancer diagnosis. Previous works show several pairs of tumor types can be successfully distinguished...
Chen-Hsiang Yeang, Sridhar Ramaswamy, Pablo Tamayo...
BMCBI
2006
146views more  BMCBI 2006»
13 years 10 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara