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    BMCBI
    2010
    109views more  BMCBI 2010»
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
    13 years 7 months ago
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
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    Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
    Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
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    BMCBI
    2008
    115views more  BMCBI 2008»
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    13 years 7 months ago
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
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    Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
    Sudhakar Jonnalagadda, Rajagopalan Srinivasan
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    BMCBI
    2010
    147views more  BMCBI 2010»
    Indirect two-sided relative ranking: a robust similarity measure for gene expression data
    13 years 7 months ago
    Indirect two-sided relative ranking: a robust similarity measure for gene expression data
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    Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
    Louis Licamele, Lise Getoor
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    BIODATAMINING
    2008
    130views more  BIODATAMINING 2008»
    Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
    13 years 7 months ago
    Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
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    Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
    Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
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    JIB
    2006
    220views more  JIB 2006»
    An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
    13 years 7 months ago
    An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
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    Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
    Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
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