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RECOMB
2002
Springer
14 years 8 months ago
A bayesian approach to transcript estimation from gene array data: the BEAM technique
We present a new statistically optimal approach to estimate transcript levels and ratios from one or more gene array experiments. The Bayesian Estimation of Array Measurements (BE...
Ron O. Dror, Jonathan G. Murnick, Nicola A. Rinald...
BMCBI
2010
130views more  BMCBI 2010»
13 years 8 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
CEC
2007
IEEE
14 years 14 days ago
Evolving hypernetwork classifiers for microRNA expression profile analysis
Abstract-- High-throughput microarrays inform us on different outlooks of the molecular mechanisms underlying the function of cells and organisms. While computational analysis for ...
Sun Kim, Soo-Jin Kim, Byoung-Tak Zhang
BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
14 years 1 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li