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BMCBI
2010
152views more  BMCBI 2010»
13 years 8 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
GECCO
2005
Springer
131views Optimization» more  GECCO 2005»
14 years 1 months ago
Multipopulation cooperative coevolutionary programming (MCCP) to enhance design innovation
This paper describes the development of an evolutionary algorithm called Multipopulation Cooperative Coevolutionary Programming (MCCP) that extends Genetic Programming (GP) to sea...
Emily M. Zechman, S. Ranji Ranjithan
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...
BMCBI
2010
110views more  BMCBI 2010»
13 years 8 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...
BMCBI
2005
159views more  BMCBI 2005»
13 years 8 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...