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BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2006
98views more  BMCBI 2006»
13 years 8 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
BMCBI
2010
190views more  BMCBI 2010»
13 years 8 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
NAR
2006
82views more  NAR 2006»
13 years 8 months ago
The RCSB PDB information portal for structural genomics
10 The RCSB Protein Data Bank (PDB) offers online tools, summary reports and target information related to the worldwide structural genomics initiatives from its portal at http://...
Andrei Kouranov, Lei Xie, Joanna de la Cruz, Li Ch...