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BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BIOCOMP
2006
13 years 8 months ago
A Heuristic Approach to Scoring Gene Clustering Algorithms
In the past decades, many clustering algorithms have been proposed for the analysis of gene expression data, but little guidance is available to help choose among them. Given the ...
Longde Yin, Chun-Hsi Huang
BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
CSB
2005
IEEE
156views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Robust Meta-classification Strategy for Cancer Diagnosis from Gene Expression Data
One of the major challenges in cancer diagnosis from microarray data is to develop robust classification models which are independent of the analysis techniques used and can combi...
Gabriela Alexe, Gyan Bhanot, Babu Venkataraghavan,...
ICML
2010
IEEE
13 years 8 months ago
High-Performance Semi-Supervised Learning using Discriminatively Constrained Generative Models
We develop a semi-supervised learning method that constrains the posterior distribution of latent variables under a generative model to satisfy a rich set of feature expectation c...
Gregory Druck, Andrew McCallum