The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
We present a global search technique for nding the global minimal conformation of a sequence in Dill's HP-lattice model5;6 . The HP-lattice model is a simpli ed model of prot...
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
In this work we present a new string similarity feature, the sparse spatial sample (SSS). An SSS is a set of short substrings at specific spatial displacements contained in the or...