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» Predicting protein folding pathways
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BIOCOMP
2006
13 years 10 months ago
Statistical Analysis of Long-Range Interactions in Proteins
We carry out a comprehensive study of long-range interactions on a large data set of non-homologous proteins. Our study reveals that the long-range interactions between amino acid...
Jinmiao Chen, Narendra S. Chaudhari
GCB
2005
Springer
117views Biometrics» more  GCB 2005»
14 years 2 months ago
Generation of 3D templates of active sites of proteins with rigid prosthetic groups
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Jean-Christophe Nebel
PRIB
2009
Springer
209views Bioinformatics» more  PRIB 2009»
14 years 3 months ago
Class Prediction from Disparate Biological Data Sources Using an Iterative Multi-Kernel Algorithm
For many biomedical modelling tasks a number of different types of data may influence predictions made by the model. An established approach to pursuing supervised learning with ...
Yiming Ying, Colin Campbell, Theodoros Damoulas, M...
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 9 months ago
Globally, unrelated protein sequences appear random
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
Daniel T. Lavelle, William R. Pearson
BMCBI
2008
140views more  BMCBI 2008»
13 years 9 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003