258 search results - page 31 / 52 » Predicting protein folding pathways |
NAR
1998
13 years 8 months ago
1998
The RAD51 gene is a eukaryotic homolog of recA, a critical component in homologous recombination and DNA repair pathways in Escherichia coli. We have cloned the RAD51 homolog from...
BMCBI
2011
13 years 20 days ago
2011
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
BMCBI
2008
13 years 9 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BIBE
2006
IEEE
14 years 3 months ago
2006
IEEE
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
JIB
2006
13 years 9 months ago
2006
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...